Theophylline is a methylpurine.Have strong heart, diuresis, dilate coronary artery, relax smooth muscle of bronchus and excited central nervous system to wait for action.Mainly used for the treatment of bronchial asthma, emphysema, bronchitis, cardiac dyspnea.
Chinese name: theophylline
Theophylline
Other names: dioxo dimethylpurine, istheobromine, Theolix, Theocin, 1, 3-dimethyxanthine
Main ingredients
Theophylline is alias: dioxy dimethylpurine;1, 3-dimethyl-3, 7-dihydro-1h-purine-2, 6-diketone;1, 3-dimethylxanthine;Theophylline hydrate;The tea base;Theophylline /1, 3-dimethylxanthine;1, 3-dimethylxanthine
Theophylline
1,3-Dimethyl-3, 7-dihydro-1h-purine-2, 6-Dione;1, 3 - dimethyl - xanthin;1 h - Purine - 2, 6 - dione, 3, 7 - dihydro - 1, 3 - dimethyl -;3, 7 - dihydro - 1, 3 - dimethyl - 1 h - purine - 6 - dione.3 h) - dione, 1, 3 - dimethyl - purine - 6 (1 h,6 - dione, 3, 7 - dihydro - 1, 3 - dimethyl - 1 h - Purine - 2;Accurbron;Acet - theocin
The CAS number: 58-55-9
Quality standard: CP
Molecular formula: C7H8N4O2
Molecular weight: 180.16
EINECS no. : 200-385-7
Density: 1.62 g/cm3
Melting point: 270-274 ℃
Boiling point :390.1°C at 760 mmHg
Flash: 189.7 ° C
Steam pressure :2.72E-06mmHg at 25°C
Storage conditions: 2-8°C
Solubility: 0.1 M HCl: Mice
Water solubility: 8.3g /L (20 & ORDM;C)
Content: 99%
Appearance: white crystalline or crystalline powder, odorless, bitter taste.
Solubility: Dissolved in water (1:120), ethanol (1:18), chloroform (1:86), alkali hydroxide, ammonia water, dilute hydrochloric acid and dilute nitric acid, slightly soluble in ether.
Usage: Theophylline is a methyl purine.Have strong heart, diuresis, dilate coronary artery, excited central classics system to wait for action.Treatment of bronchial asthma, emphysema, bronchitis, cardiac dyspnea.
The preparation methods
(1) Theocrine was prepared by the reaction of 1, 3-dimethyl-4-amino-5-formamide ureacil with sodium hydroxide solution at 90-95℃. The product was recrystallized by hot water and decolorized by activated carbon.
(2) Using ethyl cyanoacetate and dimethyl urea as raw materials, crude products were prepared by condensation, nitrification, reduction, formylation and cyclization, and recrystallized
Packing: 1kg aluminum foil bag 25kg cardboard bucket
